What is an ICR mouse?
Sophia Terry
What is an ICR mouse?
The ICR mouse is a strain of albino mice originating in SWISS and selected by Dr. Hauschka to create a fertile mouse line. Because mice of this strain have been sent to various places from the Institute of Cancer Research in the USA, the strain was named ICR after the initial letters of the institute.
Are CD1 mice outbred?
CD-1 IGS mice are outbred mice derived from a group of outbred Swiss mice developed at the Anti-Cancer Center in Lausanne, Switzerland. They were imported to the US in 1926 and to Charles River in 1959. The CD-1 IGS mice are generally used for genetics, toxicology, pharmacology, and aging research.
Are CD1 mice immunocompetent?
CD-1® Nude Mouse Details Developed from the transfer of the nude gene from Crl:NU-Foxn1nu to a CD-1® mouse through a series of crosses and backcrosses beginning in 1979 at Charles River Laboratories, Wilmington, MA. The animal lacks a thymus, is unable to produce T-cells, and is therefore immunodeficient.
What is C3H?
C3H/HeJ mice, commonly called C3H, are used as a general purpose strain in a wide variety of research areas including cancer, infectious disease, sensorineural, and cardiovascular biology research.
What does cd1 mice stand for?
CD-1® IGS Mouse Details The original group of Swiss mice that served as progenitors of this stock consisted of two male and seven female albino mice derived from a non-inbred stock in the laboratory of Dr. de Coulon, Centre Anticancereux Romand, Lausanne, Switzerland.
What is the difference between inbred and outbred mice?
Genetically, there are two major classes of laboratory mice: inbred and outbred. Inbred mice are genetically homogeneous and there is very little variation or heterogeneity within a pure inbred strain. Outbred mice are bred specifically to maximize genetic diversity and heterozygosity within a population.
Why ICR mice are used in research?
ICR mice are one the most commonly available outbred population because they have good reproductive performance, are inexpensive, robust, and grow rapidly [5,6].
What is cdcd-1 IGS mouse?
CD-1® IGS Mouse | Charles River Laboratories. The original group of Swiss mice that served as progenitors of this stock consisted of two male and seven female albino mice derived from a non-inbred stock in the laboratory of Dr. de Coulon, Centre Anticancereux Romand, Lausanne, Switzerland.
Where did cdcd-1 mice come from?
CD-1® IGS Mouse Details. The original group of Swiss mice that served as progenitors of this stock consisted of two male and seven female albino mice derived from a non-inbred stock in the laboratory of Dr. de Coulon, Centre Anticancereux Romand, Lausanne, Switzerland. These animals were imported into the United States by Dr.
What is the origin of the ha/ICR mouse model?
Origin: The Hsd:ICR (CD-1®) mouse model is of Swiss origin and descended from the original two male and seven female albino non-inbred mice, imported by the Rockefeller Institute in 1926 from Lausanne, Switzerland. Descendants were distributed worldwide and the Ha/ICR was established in 1948 at the Institute of Cancer Research (ICR).
Is the cd1-elite mouse VAF or SOPF?
Note: We also offer the CD1-Elite Mouse with a VAF/Elite ® health profile (bred in US) and the CD1 -SOPF Mouse with a SOPF health profile (bred in France). Growth chart data should be used as a guideline only.
