How rare is transposition of the great arteries?

Transposition of the great arteries (TGA), also referred to as complete transposition, is a congenital cardiac malformation characterised by atrioventricular concordance and ventriculoarterial (VA) discordance. The incidence is estimated at 1 in 3,500–5,000 live births, with a male-to-female ratio 1.5 to 3.2:1.

What percent of children have transposition of the great arteries?

The Center for Disease Control (CDC) estimated that each year, 1901 babies in the United States are born with TGA or an approximate of 5 in 10000 babies born yearly with it[10]. It is present in 5%-7% of all patients with congenital heart disease[11].

What is the survival rate of transposition of the great arteries?

Today, the survival rate for infants with transposition of the great arteries is greater than 90%.

How common is TGA in newborns?

The Centers for Disease Control and Prevention (CDC) estimates that about 1,153 babies are born with TGA each year in the United States. This means that every 1 in 3,413 babies born in the US is affected by this defect.

Is transposition of the great arteries fatal?

Transposition of the great arteries or TGA is a potentially fatal congenital heart malformation where the pulmonary artery and the aorta are switched. The switch means that the aorta, which normally carries oxygenated blood, carries deoxygenated blood.

Can TGA be detected before birth?

TGA is sometimes diagnosed by fetal ultrasound before the baby is born. First trimester screening for chromosomal abnormalities is a good screening tool to identify patients who might be at an increased risk for cardiac defects.

Is transposition of the great vessels fatal?

How common is transposition of the great vessels?

Occurrence. The Centers for Disease Control and Prevention (CDC) estimates that about 1,153 babies are born with TGA each year in the United States. This means that every 1 in 3,413 babies born in the US is affected by this defect.

Is transposition of the great vessels hereditary?

Background Transposition of the great arteries (TGA) is considered to be associated only rarely with genetic syndromes and to have a low risk of precurrence among relatives of affected patients.

How can a sonographer rule out transposition of the great vessels?

The diagnosis of TGA can be made by carefully and appropriately evaluating the anatomic locations of cardiac chambers and the connections between the atria, ventricles, and great arteries at this gestational age with high-resolution ultrasound.